Atuveciclib (BAY-1143572)

Name: Atuveciclib (BAY-1143572)
Brand: Selleckchem
Price: 128.0 USD
Availability: InStock

Vendor: Selleckchem

Type: Cell Cycle

SKU: S8727-2mg

$128.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Cell Cycle

Cas number

1414943-88-6

Formula

C18H18FN5O2S

Small target

CDK

Smiles

COC1=C(C=CC(=C1)F)C2=NC(=NC=N2)NC3=CC=CC(=C3)CS(=N)(=O)C

Storage conditions

3 years -20°C powder

Background

Atuveciclib (BAY-1143572) is a potent and highly selective PTEFb/CDK9 inhibitor with IC50 values of 13 nM for CDK9/CycT and the ratio of IC50 values for CDK2/CDK9 is about 100. Outside the CDK family, It inhibits GSK3 kinase with IC50 values of 45 nM and 87 nM for GSK3α and GSK3β respectively.

Atuveciclib (BAY-1143572)

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Product Overview

Background

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