Naporafenib (LXH254) chemical structure

Naporafenib (LXH254)

Vendor: Selleckchem

Type: MAPK

SKU: S8745-2mg

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Naporafenib (LXH254) chemical structure

Naporafenib (LXH254)

$118.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
MAPK
Cas number
1800398-38-2
Formula
C25H25F3N4O4
Small target
Raf
Smiles
CC1=C(C=C(C=C1)NC(=O)C2=CC(=NC=C2)C(F)(F)F)C3=CC(=NC(=C3)OCCO)N4CCOCC4
Storage conditions
3 years -20°C powder
Scientific background
Naporafenib (LXH254) is a type II ATP-competitive inhibitor that inhibits both B- and CRAF kinase activities at picomolar concentrations with a high degree of selectivity against a panel of 456 human kinases and in cell-based assays.
Technical documents

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