AZD3229 chemical structure

AZD3229

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S8780-2mg

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For research use only — not intended for clinical or diagnostic purposes.
AZD3229 chemical structure

AZD3229

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
2248003-60-1
Formula
C24H26FN7O3
Small target
c-Kit
Smiles
CC(C)C1=CN(N=N1)CC(=O)NC2=CC=C(C=C2)NC3=NC=NC4=C3C(=CC(=C4)OCCOC)F
Storage conditions
3 years -20°C powder
Scientific background
AZD3229 is a potent, pan-Kit (c-Kit) mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant Kit (c-Kit) driven Ba/F3 cell lines (GI50=1-50 nM), with good margin to KDR-driven effects. It also inhibits PDGFR mutants (Tel-PDGFRα, Tel-PDGFRβ, V561D/D842V).
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