YKL-5-124 chemical structure

YKL-5-124

Vendor: Selleckchem

Type: Cell Cycle

SKU: S8863-5mg

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$278.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
YKL-5-124 chemical structure

YKL-5-124

$278.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Cell Cycle
Cas number
1957203-01-8
Formula
C28H33N7O3
Small target
CDK
Smiles
CC1(C2=C(CN1C(=O)NC(CN(C)C)C3=CC=CC=C3)C(=NN2)NC(=O)C4=CC=C(C=C4)NC(=O)C=C)C
Storage conditions
3 years -20°C powder
Scientific background
YKL-5-124 is a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for inhibiting CDK7/Mat1/CycH, CDK2 and CDK9 respectively. It displays biochemical and cellular selectivity for CDK7 over CDK12/13.
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