BAY-985 chemical structure

BAY-985

Vendor: Selleckchem

Type: Immunology & Inflammation

SKU: S8935-5mg

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$428.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
BAY-985 chemical structure

BAY-985

$428.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Immunology & Inflammation
Cas number
2409479-29-2
Formula
C27H30F3N9O
Small target
TBK1
Smiles
CC(C1=CC(=NC=C1)NC2=NC3=C(N2)C=C(C=C3)C4=CC(=NC=N4)N(C)C)N5CCN(CC5)C(=O)CC(F)(F)F
Storage conditions
3 years -20°C powder
Scientific background
BAY-985 is a potent and highly selective TBK1/IKKε inhibitor. BAY-985 shows high potency toward TBK1 (IC50 = 2 nM, low ATP assay; 30 nM, high ATP assay) and IKKε(IC50 = 2 nM), as well as high potency in the mechanistic pIRF3 assay (IC50 = 74 nM), and an antiproliferative effect on SK-MEL-2 cells (IC50 = 900 nM).
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