BRD3308 chemical structure

BRD3308

Vendor: Selleckchem

Type: DNA Damage/DNA Repair

SKU: S8962-100mg

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$613.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
BRD3308 chemical structure

BRD3308

$613.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
DNA Damage/DNA Repair
Cas number
1550053-02-5
Formula
C15H14FN3O2
Small target
HDAC
Smiles
CC(=O)NC1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)F)N
Storage conditions
3 years -20°C powder
Scientific background
BRD3308 is a potant and highly selective inhibitor of HDAC3 with IC50 of 54 nM, 1.26 μM and 1.34 μM for HDAC3, HDAC1 and HDAC2, respectively. BRD3308 activates HIV-1 transcription. BRD3308 suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines (glucolipotoxic stress) and increases functional insulin release.
Technical documents

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