Homoharringtonine (HHT)

Name: Homoharringtonine (HHT)
Brand: Selleckchem
Price: 110.0 USD
Availability: InStock

Vendor: Selleckchem

Type: Apoptosis

SKU: S9015-1mg

$110.00 USD

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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Big target

Apoptosis

Cas number

26833-87-4

Formula

C29H39NO9

Small target

STAT

Smiles

CC(C)(CCCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O

Storage conditions

3 years -20°C powder

Synonyms

CGX-635, Myelostat, NSC 141633

Background

Homoharringtonine (HHT), a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversiblely inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression.

Homoharringtonine (HHT)

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Product Overview

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