Berbamine chemical structure

Berbamine

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S9141-5mg

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Berbamine chemical structure

Berbamine

$110.00 USD

THE SCIENCE, IN DETAIL

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Specifications
Big target
Protein Tyrosine Kinase
Cas number
478-61-5
Formula
C37H40N2O6
Small target
Bcr-Abl
Smiles
CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)O)OC
Storage conditions
3 years -20°C powder
Synonyms
BA, BBM
Scientific background
Berbamine (BA), a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA) induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca²⁺/calmodulin-dependent protein kinase II (CaMKII).
Technical documents

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