UNC2025 chemical structure

UNC2025

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S9662-5mg

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For research use only — not intended for clinical or diagnostic purposes.
UNC2025 chemical structure

UNC2025

$110.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1429881-91-3
Formula
C28H40N6O
Small target
FLT3
Smiles
CCCCNC1=NC=C2C(=CN(C2=N1)C3CCC(CC3)O)C4=CC=C(C=C4)CN5CCN(CC5)C
Storage conditions
3 years -20°C powder
Scientific background
UNC2025 is a potent and orally active dual inhibitor of FLT3 and MER with IC50 of 0.35 nM and 0.46 nM, respectively. UNC2025 also inhibits AXL, TRKA, TRKC, QIK, TYRO3, SLK, NuaK1, Kit (c-Kit) and Met (c-Met) with IC50 of 1.65 nM, 1.67 nM, 4.38 nM, 5.75 nM, 5.83 nM, 6.14 nM, 7.97 nM, 8.18 nM and 364 nM, respectively.
Technical documents

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