PKR-IN-C16 chemical structure

PKR-IN-C16

Vendor: Selleckchem

Type: Immunology & Inflammation

SKU: S9668-5mg

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PKR-IN-C16 chemical structure

PKR-IN-C16

$128.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Immunology & Inflammation
Cas number
608512-97-6
Formula
C13H8N4OS
Small target
PKR
Smiles
C1=CC2=C(C3=C1NC(=O)C3=CC4=CN=CN4)SC=N2
Storage conditions
3 years -20°C powder
Synonyms
imoxin, C16, Imidazolo-oxindole PKR inhibitor C16
Scientific background
PKR-IN-C16 (imoxin, C16, Imidazolo-oxindole PKR inhibitor C16) is a specific inhibitor of RNA-dependent protein kinase (PKR, Protein Kinase R, EIF2AK2). PKR-IN-C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component.
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