Tapinarof chemical structure

Tapinarof

Vendor: Selleckchem

Type: Immunology & Inflammation

SKU: S9700-5mg

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$185.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Tapinarof chemical structure

Tapinarof

$185.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Immunology & Inflammation
Cas number
79338-84-4
Formula
C17H18O2
Small target
AhR
Smiles
CC(C)C1=C(O)C=C(\C=C\C2=CC=CC=C2)C=C1O
Storage conditions
3 years -20°C powder
Synonyms
GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505
Scientific background
Tapinarof (GSK2894512, Benvitimod, WBI 1001, DHPS, DMVT 505) is a natural agonist of aryl hydrocarbon receptor (AhR) and induces nuclear translocation of AhR in immortalized keratinocytes (HaCaT) with EC50 of 0.16 nM. Tapinarof induces cellular apoptosis in CD4+ T cells in a dosedependent manner with IC50 of 5.2 μM.
Technical documents

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