Lanraplenib (GS-SYK) chemical structure

Lanraplenib (GS-SYK)

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S9715-5mg

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Lanraplenib (GS-SYK) chemical structure

Lanraplenib (GS-SYK)

$127.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
1800046-95-0
Formula
C23H25N9O
Small target
Syk
Smiles
NC1=CN=CC(=N1)C2=C[N]3C=CN=C3C(=N2)NC4=CC=C(C=C4)N5CCN(CC5)C6COC6
Storage conditions
3 years -20°C powder
Synonyms
GS-9876
Scientific background
Lanraplenib (GS-SYK)is a potent, highly selective and orally active inhibitor of Spleen Tyrosine Kinase (SYK) with IC50 of 9.5 nM. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.
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