Rimiducid (AP1903) chemical structure

Rimiducid (AP1903)

Vendor: Selleckchem

Type: Apoptosis

SKU: S9726-5mg

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For research use only — not intended for clinical or diagnostic purposes.
Rimiducid (AP1903) chemical structure

Rimiducid (AP1903)

$269.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Apoptosis
Cas number
195514-63-7
Formula
C78H98N4O20
Small target
FKBP
Smiles
CCC(C(=O)N1CCCCC1C(=O)OC(CCC2=CC(=C(OC)C=C2)OC)C3=CC(=CC=C3)OCC(=O)NCCNC(=O)COC4=CC=CC(=C4)C(CCC5=CC(=C(OC)C=C5)OC)OC(=O)C6CCCCN6C(=O)C(CC)C7=CC(=C(OC)C(=C7)OC)OC)C8=CC(=C(OC)C(=C8)OC)OC
Storage conditions
3 years -20°C powder
Scientific background
Rimiducid (AP1903) is a chemical protein dimerizer and binds tightly to the target FKBP fusion protein while binding minimally to the abundant natural FKBP. Rimiducid elicites potent and dose-dependent apoptosis of cells in culture expressing dimerizer-dependent Fas constructs, with an EC50 of ≈0.1 nM.
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