Indisulam chemical structure

Indisulam

Vendor: Selleckchem

Type: Metabolism

SKU: S9742-5mg

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Indisulam chemical structure

Indisulam

$110.00 USD

THE SCIENCE, IN DETAIL

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Specifications
Big target
Metabolism
Cas number
165668-41-7
Formula
C14H12ClN3O4S2
Small target
Carbonic Anhydrase
Smiles
N[S](=O)(=O)C1=CC=C(C=C1)[S](=O)(=O)NC2=C3[NH]C=C(Cl)C3=CC=C2
Storage conditions
3 years -20°C powder
Synonyms
E7070
Scientific background
Indisulam (E7070), a sulfonamide anticancer agent, is a potent carbonic anhydrase (CA) inhibitor that inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. Indisulam suppresses the expression of cyclin E and phosphorylation of CDK2, both of which are essential for the G1 to S transition.
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