HM43239 chemical structure

HM43239

Vendor: Selleckchem

Type: Protein Tyrosine Kinase

SKU: S9892-5mg

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For research use only — not intended for clinical or diagnostic purposes.
HM43239 chemical structure

HM43239

$119.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Big target
Protein Tyrosine Kinase
Cas number
2569527-64-4
Formula
C29H33ClN6
Small target
FLT3
Smiles
CC1CN(CC(C)N1)CC2=CC(=CC(=C2)NC3=NC=C(Cl)C(=N3)C4=C[NH]C5=C4C=CC(=C5)C)C6CC6
Storage conditions
3 years -20°C powder
Scientific background
HM43239 is a novel potent small molecule FLT3 inhibitor that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. IC50s’ of HM43239 against FLT3 WT, FLT3 ITD and FLT3 D835Y kinases are 1.1 nM, 1.8 nM and 1.0 nM, respectively.
Technical documents

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