SFTI-1

Vendor: Abmole

Type: Molecular

SKU: M40668

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$1,104.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
SFTI-1

SFTI-1

$1,104.00 USD

THE SCIENCE, IN DETAIL

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Specifications
Bioactivity
SFTI-1 is a head-to-tail bicyclic peptide with a disulfide bond that inhibits the serine protease trypsin with subnanomolar levels of inhibition constants. It can be used as a protease inhibitor or as a molecular grafting scaffold. In addition, by introducing a known tetrapeptide pharmacophore into the bicyclic SFTI-1, a potent ligand for melanocortin can be created.
Casnumber
245080-24-4
Formula
C67H104N18O18S2
Mw
1513.78
Psmiles
CCC(C)C1C(=O)NC2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N3CCCC3C(=O)N4CCCC4C(=O)N1)C(C)CC)CO)CCCCN)C(C)O)NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C5CCCN5C(=O)C(NC2=O)CC6=CC=CC=C6)CC(=O)O)CCCN=C(N)NCCC(C)C1C(=O)NC2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N3CCCC3C(=O)N4CCCC4C(=O)N1)C(C)CC)CO)CCCCN)C(C)O)NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C5CCCN5C(=O)C(NC2=O)CC6=CC=CC=C6)CC(=O)O)CCCN=C(N)N
Purity
>99.0%
Target synonyms
Sunflower trypsin inhibitor 1
Technical documents

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