Siah-1/2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES3442
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cytoplasm. Nucleus. Predominantly cytoplasmic. Partially nuclear.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
6477/6478
Human swiss prot no
Q8IUQ4/O43255
Immunogen
The antiserum was produced against synthesized peptide derived from human SIAH1. AA range:181-230
Isotype
IgG
Observed band
34kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008],
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More Info
More Info
Siah-1/2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
