Simvastatin (MK 733)

Vendor: Abmole

Type: Molecular

SKU: M3497

$132.25 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Simvastatin (MK-0733, MK 733) is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM in cell-free assays. Simvastatin induces ferroptosis, mitophagy, autophagy and apoptosis. Simvastatin inhibits exosome release. Prior to use in cell assays, Simvastatin needs to be activated by NaOH in EtOH treatment.
Casnumber
79902-63-9
Formula
C25H38O5
Mw
418.57
Psmiles
CCC(C)(C)C(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C12
Purity
99.41%
Solubility
DMSO 80 mg/mL
Target synonyms
MK 733; MK-0733
Simvastatin (MK 733)

Simvastatin (MK 733)

$132.25 USD