Siramesine

Vendor: Abmole

Type: Molecular

SKU: M2592

$1,656.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Siramesine (Lu 28-179) is a potent sigma-2 receptor agonist. Siramesine has a subnanomolar affinity for sigma-2 receptors (IC50=0.12 nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC50=17 nM). Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes.
Casnumber
147817-50-3
Formula
C30H31FN2O
Mw
454.58
Psmiles
C1CN(CCC12C3=CC=CC=C3CO2)CCCCC4=CN(C5=CC=CC=C54)C6=CC=C(C=C6)F
Purity
>99%
Solubility
DMSO
Target synonyms
Lu 28-179
Siramesine

Siramesine

$1,656.00 USD