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Siremadlin

Siremadlin

Regular price $1,207.50 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Siremadlin (HDM201) is a novel, highly potent and selective inhibitor of the p53-Mdm2 interaction with affinity constant for Mdm2 in the picomolar range and a selectivity ratio greater than 10000-fold vs Mdm4.
Casnumber
1448867-41-1
Formula
C26H24Cl2N6O4
Mw
555.41
Psmiles
CC(C)N1C2=C(C(=O)N(C2C3=CC=C(C=C3)Cl)C4=CC(=CN(C4=O)C)Cl)N=C1C5=CN=C(N=C5OC)OC
Purity
>99.0%
Solubility
100 mg/mL in DMSO
Target synonyms
NVP-HDM201; HDM201
Technical documents

Documents

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