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SIRT7 inhibitor 97491

SIRT7 inhibitor 97491

Regular price $414.00 USD
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THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway..
Casnumber
1807758-81-1
Formula
C15H12ClN3O
Mw
285.73
Psmiles
NC1=CC=CC(=C1)NC2=NC=C(O2)C3=CC=C(Cl)C=C3
Purity
98.21%
Solubility
DMSO 500 mg/mL (ultrasonic)
Technical documents

Documents

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