SKF-83566

Vendor: Abmole

Type: Molecular

SKU: M30989

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$172.50 USD
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For research use only — not intended for clinical or diagnostic purposes.
SKF-83566

SKF-83566

$172.50 USD

THE SCIENCE, IN DETAIL

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Specifications
Bioactivity
SKF-83566 is a potent, blood-brain permeable and orally active D1-like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor (Ki=11 nM). SKF-83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5.7 μM. SKF-83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta. SKF-83566 can be used for research of parkinson’s disease and nicotine craving alleviation.
Casnumber
99295-33-7
Formula
C17H18BrNO
Mw
332.23
Psmiles
CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Br
Purity
≥99.0%
Solubility
DMSO 30 mg/mL (ultrasonic)
Technical documents

Documents

Coa

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