SKI-178

Vendor: Abmole

Type: Molecular

SKU: M13356

$120.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
SKI-178 is a potent sphingosine kinase-1 (SphK1) and SphK2 inhibitor. In acute myeloid leukemia (AML) cell lines, the IC50 range is about 500 nm-1 μM. Ski-178 induces apoptosis of human acute myeloid leukemia cells in a CDK1-dependent manner.
Casnumber
1259484-97-3
Formula
C21H22N4O4
Mw
394.42
Psmiles
COC1=CC=C(C=C1)C2=N[NH]C(=C2)C(=O)N\N=C(C)\C3=CC(=C(OC)C=C3)OC
Purity
>98%
Solubility
DMSO ≥ 40 mg/mL
SKI-178

SKI-178

$120.75 USD