SNX5 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES10302
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Endosome . Early endosome . Early endosome membrane ; Peripheral membrane protein; Cytoplasmic side. Cell membrane ; Peripheral membrane protein; Cytoplasmic side . Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cell projection, phagocytic cup. Cell projection, ruffle. Recruited to the plasma membrane after EGF stimulation, which leads to increased levels of phosphatidylinositol 3,4-bisphosphate (PdtIns(3,4)P2) (PubMed:15561769). Detected on macropinosomes (PubMed:16968745, PubMed:21048941). Targeted to membrane ruffles in response to EGFR stimulation. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
27131
Human swiss prot no
Q9Y5X3
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Observed band
44kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013],
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Product Citations
Product Citations
More Info
More Info
SNX5 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

