Sophocarpine monohydrate

Vendor: Abmole

Type: Molecular

SKU: M3913

$63.25 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Sophocarpine monohydrate is a HERG K+ channel blocker with IC50 of 100-300 μM and Na+ channel inward current inhibitor. Sophocarpine monohydrate is a PTEN activator and an inhibitor of PI3K/Akt, MEK/ERK, and NF-κB signaling pathways. Sophocarpine monohydrate upregulates PTEN expression and inhibits PI3K/Akt phosphorylation, arrests tumor cell cycle and induces apoptosis. Sophocarpine monohydrate inhibits MEK/ERK phosphorylation and VEGF secretion, reducing tumor cell migration.
Casnumber
145572-44-7
Formula
C15H24N2O2
Mw
264.36
Psmiles
O.O=C1C=CCC2C3CCCN4CCCC(CN12)C34
Purity
>99.0%
Solubility
DMSO 90 mg/mL
Sophocarpine monohydrate

Sophocarpine monohydrate

$63.25 USD