Sorafenib (BAY 43-9006)

Vendor: Abmole

Type: Molecular

SKU: M3026

$51.75 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Sorafenib (BAY 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively. Sorafenib is a multikinase inhibitor with IC50 values of 15 nM, 20 nM, 57 nM and 58 nM for VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib induces autophagy and apoptosis. Sorafenib is a ferroptosis activator.
Casnumber
284461-73-0
Formula
C21H16ClF3N4O3
Mw
464.82
Psmiles
CNC(=O)C1=CC(=CC=N1)OC2=CC=C(NC(=O)NC3=CC=C(Cl)C(=C3)C(F)(F)F)C=C2
Purity
99.87%
Solubility
DMSO 45 mg/mL
Target synonyms
BAY 43-9006
Sorafenib (BAY 43-9006)

Sorafenib (BAY 43-9006)

$51.75 USD