SPAST rabbit pAb
Vendor: ELK Biotechnology
SKU: ES12999
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
Membrane ; Peripheral membrane protein . Endoplasmic reticulum . Midbody . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton . Cytoplasm, perinuclear region . Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasm . Forms an intramembrane hairpin-like structure in the membrane (PubMed:20200447). Localization to the centrosome is independent of microtubules (PubMed:15891913). Localizes to the midbody of dividing cells, and this requires CHMP1B (PubMed:18997780). Enriched in the distal axons and branches of postmitotic neurons (PubMed:15269182). .; [Isoform 1]: Endoplasmic reticulum membrane ; Peripheral membrane protein . Nucleus membrane . Lipid droplet . Cytoplasm, cytoskeleton . Endosome . Forms an intramembrane hairpin-like structure in the mem
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
6683
Human swiss prot no
Q9UBP0
Immunogen
Synthesized peptide derived from human SPAST AA range: 163-213
Isotype
IgG
Product weight
0.005kg
Reactivity
Human; Mouse;Rat
Recommended dilutions
WB 1：500-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4. [provided by RefSeq, Jul 2008],
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More Info
More Info
SPAST rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
