Splicing factor 1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES3486
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Nucleus.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
7536
Human swiss prot no
Q15637
Immunogen
The antiserum was produced against synthesized peptide derived from human SF1. AA range:48-97
Isotype
IgG
Observed band
68kD
Product weight
0.005kg
Reactivity
Human;Mouse
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016],
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Product Citations
Product Citations
More Info
More Info
Splicing factor 1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
