SPTA1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES12973
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
6708
Human swiss prot no
P02549
Immunogen
Synthesized peptide derived from human SPTA1 AA range: 1217-1267
Isotype
IgG
Product weight
0.005kg
Reactivity
Human; Mouse
Recommended dilutions
WB 1：500-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. [provided by RefSeq, Jul 2008],
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More Info
More Info
SPTA1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
