SPTN2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES12970
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC
Cellular localization
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
6712
Human swiss prot no
O15020
Immunogen
Synthesized peptide derived from human SPTN2 AA range: 644-694
Isotype
IgG
Product weight
0.005kg
Reactivity
Human;Rat
Recommended dilutions
WB 1:500-2000;IHC-p 1:50-300
Source
Rabbit
Storage
-20°C/1 year
Background
Background
Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009],
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More Info
More Info
SPTN2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
