SRBP2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES8983
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
[Sterol regulatory element-binding protein 2]: Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, COPII-coated vesicle membrane ; Multi-pass membrane protein . At high sterol concentrations, the SCAP-SREBP is retained in the endoplasmic reticulum (PubMed:32322062). Low sterol concentrations promote recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi, where it is processed (PubMed:32322062). .; [Processed sterol regulatory element-binding protein 2]: Nucleus . Transported into the nucleus with the help of importin-beta. Dimerization of the bHLH domain is a prerequisite for importin beta-dependent nuclear import. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
6721
Human swiss prot no
Q12772
Immunogen
Synthesized peptide derived from human protein . at AA range: 390-470
Isotype
IgG
Observed band
125kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
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Product Citations
Product Citations
More Info
More Info
SRBP2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

