SRBS2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES12961
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
Cytoplasm, perinuclear region . Apical cell membrane . Cell junction, focal adhesion . Cell projection, lamellipodium . Found at the Z-disk sarcomeres, stress fibers, dense bodies and focal adhesion. In pancreatic acinar cells, localized preferentially to the apical membrane. Colocalized with vinculin and filamentous actin at focal adhesions and lamellipodia of pancreatic cells. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
8470
Human swiss prot no
O94875
Immunogen
Synthesized peptide derived from human SRBS2 AA range: 794-844
Isotype
IgG
Product weight
0.005kg
Reactivity
Human; Mouse;Rat
Recommended dilutions
WB 1：500-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
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More Info
More Info
SRBS2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
