SRF (phospho Ser77) rabbit pAb

Name: SRF (phospho Ser77) rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES7274

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;IHC;IF;ELISA

Cellular localization

Nucleus .

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

6722

Human swiss prot no

P11831

Immunogen

The antiserum was produced against synthesized peptide derived from human SRF around the phosphorylation site of Ser77. AA range:41-90

Isotype

IgG

Observed band

52kD

Product weight

0.005kg

Reactivity

Human;Mouse

Recommended dilutions

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014],

SRF (phospho Ser77) rabbit pAb

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