SRI-41315

Vendor: Abmole

Type: Molecular

SKU: M54648

$212.75 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
SRI-41315 inhibits PTCs (premature termination codons) associated with cystic fibrosis in permanent and primary human bronchial epithelial cells by inducing a prolonged stoppage of the termination codon, restoring the expression and function of cystic fibrosis transmembrane conductance regulator (CFTR). In addition, SRI-41315 enhances aminoglycoside-mediated passaging, leading to a synergistic increase in CFTR activity.
Casnumber
1613509-49-1
Formula
C22H19N3O2
Mw
357.00
Psmiles
CN1C2=CC=CC=C2C(=O)C3=C1N=C(N(C3=O)C4=CC=CC=C4)C5CCC5
Purity
>99.0%
Solubility
DMSO 20.83 mg/mL
SRI-41315

SRI-41315

$212.75 USD