Synta66

Vendor: Abmole

Type: Molecular

SKU: M8747

$184.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Synta66 (S66) is a CRAC (Ca2+ release-activated Ca2+) channel inhibitor that blocks SOCE (store-operated Ca2+ entry) upon Ca2+ depletion from intracellular stores by thapsigargin in human vascular smooth muscle cells (VSMCs) with high potency (IC50 = 26 nM & 43 nM based on maximum Ca2+ level & rate of increase, respectly).
Casnumber
835904-51-3
Formula
C20H17FN2O3
Mw
352.36
Psmiles
COC1=CC(=C(C=C1)OC)C2=CC=C(C=C2)NC(=O)C3=C(C=NC=C3)F
Purity
>98%
Solubility
DMSO: 20 mg/mL
Synta66

Synta66

$184.00 USD