TAF II p135/p105 rabbit pAb

Name: TAF II p135/p105 rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES7335

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;IHC;IF;ELISA

Cellular localization

Nucleus.

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

6874/6875

Human swiss prot no

O00268/Q92750

Immunogen

The antiserum was produced against synthesized peptide derived from human TAF4. AA range:941-990

Isotype

IgG

Observed band

110kD

Product weight

0.005kg

Reactivity

Human;Mouse

Recommended dilutions

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that has been shown to potentiate transcriptional activation by retinoic acid, thyroid hormone and

TAF II p135/p105 rabbit pAb

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