TAK-242 (Resatorvid)

Vendor: Abmole

Type: Molecular

SKU: M4838

$193.20 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Resatorvid (TAK-242) is a selective TLR4 signaling inhibitor. Resatorvid inhibited the production of NO, TNF-α and IL-6 with IC50 values of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid down-regulates the expression of MyD88 and TRIF signaling molecules downstream of TLR4. Resatorvid inhibits autophagy and plays a key role in a variety of inflammatory diseases.
Casnumber
243984-11-4
Formula
C15H17ClFNO4S
Mw
361.82
Psmiles
CCOC(=O)C1=CCCCC1[S](=O)(=O)NC2=C(Cl)C=C(F)C=C2
Purity
99.91%
Solubility
DMSO 80 mg/mL
Target synonyms
Resatorvid; CLI-095
TAK-242 (Resatorvid)

TAK-242 (Resatorvid)

$193.20 USD