Taletrectinib

Vendor: Abmole

Type: Molecular

SKU: M10936

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$322.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Taletrectinib

Taletrectinib

$322.00 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Taletrectinib (DS-6051b) is a potent orally active next-generation selective ROS1/NTRK inhibitor. Taletrectinib is 0.207, 0.622, 2.28, and 0.98 nM, respectively IC50 It has a strong inhibitory effect on recombinant ROS1, NTRK1, NTRK2 and NTRK3. Taletrectinib also inhibits ROS1 G2032R and other ANTI-Crizotinib ROS1 mutants.
Casnumber
1505515-69-4
Formula
C29H34FN5O5
Mw
551.62
Psmiles
CC(N)COC1=CC=C(C=C1)C2=CN=C3C=CC(=N[N]23)NC(C)C4=CC(=CC=C4)F.OC(=O)CCCCC(O)=O
Purity
>99.0%
Solubility
DMSO ≥ 40 mg/mL
Target synonyms
DS-6051b; AB-106; IBI-344
Technical documents

Documents

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