TAP1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES11972
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein . The transmembrane segments seem to form a pore in the membrane.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
6890
Human swiss prot no
Q03518
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Observed band
88kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014],
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Product Citations
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More Info
More Info
TAP1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
