TAP2 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES12816
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein . The transmembrane segments seem to form a pore in the membrane.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
6891
Human swiss prot no
Q03519
Immunogen
Synthesized peptide derived from human TAP2 AA range: 182-232
Isotype
IgG
Product weight
0.005kg
Reactivity
Human; Mouse;Rat
Recommended dilutions
WB 1：500-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014],
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More Info
More Info
TAP2 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
