Temuterkib

Vendor: Abmole

Type: Molecular

SKU: M11529

$408.25 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Temuterkib (LY3214996) is a selective, novel erK1/2 inhibitor with an IC50 of 5 nM against ERK1 and ERK2. It can effectively inhibit intracellular P-RSK1 in cancer cell lines with BRAF and RAS mutations. Temuterkib has strong antitumor activity in cancer models with altered MAPK pathways.
Casnumber
1951483-29-6
Formula
C22H27N7O2S
Mw
453.56
Psmiles
C[N]1N=CC=C1NC2=NC(=CC=N2)C3=CC4=C(S3)C(C)(C)N(CCN5CCOCC5)C4=O
Purity
99.52%
Solubility
DMSO ≥ 20 mg/mL
Target synonyms
LY3214996
Temuterkib

Temuterkib

$408.25 USD