TH 1020

Vendor: Abmole

Type: Molecular

SKU: M7408

$805.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
TH1020 is an effective selective toll-like receptor 5 (TLR5)/ flagellin complex antagonist with IC50 of 0.85 μM. TH1020 inhibits flagellin-induced TLR5 signal transduction, but has no effect on TLR2, TLR3, TLR4, TLR7 and TLR8.
Casnumber
1841460-82-9
Formula
C23H15N7S2
Mw
453.54
Psmiles
C1=CC=C(C=C1)CN2C(=NN=C2SC3=NC=NC4=C3SC5=C4C=CC=N5)C6=CC=NC=C6
Purity
>98%
Solubility
DMSO 2.27 mg/mL (with gentle warming)
TH 1020

TH 1020

$805.00 USD