TH-Z145

Vendor: Abmole

Type: Molecular

SKU: M55216

$241.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
TH-Z145 is a lipophilic GGPPS inhibitor (GGPPS IC50 = 210 nM). TH-Z145 is a very lipophilic bisphosphonate that lacks the cationic center essential for FPPS inhibition and is thus a specific GGPPS inhibitor (FPPS IC50 >30 mM). TH-Z145 exhibited strong prophylactic effects in a pathogenic influenza model.
Casnumber
2260887-57-6
Formula
C16H28O7P2
Mw
394.34
Psmiles
CCCCCCCCOC1=CC=CC(=C1)CC(P(=O)(O)O)P(=O)(O)O
Purity
>95.0%
Solubility
DMSO 90 mg/mL
Target synonyms
THZ145
TH-Z145

TH-Z145

$241.50 USD