Tirapazamine

Vendor: Abmole

Type: Molecular

SKU: M8392

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$149.50 USD
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For research use only — not intended for clinical or diagnostic purposes.
Tirapazamine

Tirapazamine

$149.50 USD

THE SCIENCE, IN DETAIL

Know your product.

Specifications
Bioactivity
Tirapazamine (TPZ，SR-4233, WIN 59075) is the first hypoxia-activated prodrug. Tirapazamine kills hypoxic cells by inducing chromosome aberrations and DNA double-strand breaks. Tirapazamine induced cell cycle arrest and apoptosis, and down-regulated HIF-1α, CA-IX and VEGF expression.
Casnumber
27314-97-2
Formula
C7H6N4O2
Mw
178.15
Psmiles
NC1=[N+]([O-])C2=CC=CC=C2[N+](=N1)[O-]
Purity
99.43%
Solubility
DMSO ≥ 20 mg/mL
Target synonyms
SR259075; SR4233; Win59075; SML 0552; Tirazone; TPZ
Technical documents

Documents

Coa

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