TNF-α rabbit pAb
Vendor: ELK Biotechnology
SKU: ES3623
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cell membrane ; Single-pass type II membrane protein .; [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein.; [Tumor necrosis factor, soluble form]: Secreted .; [C-domain 1]: Secreted.; [C-domain 2]: Secreted.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
7124
Human swiss prot no
P01375
Immunogen
The antiserum was produced against synthesized peptide derived from human TNFA. AA range:141-190
Isotype
IgG
Observed band
16kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008],
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Product Citations
Product Citations
More Info
More Info
TNF-α rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
