TNO155

Vendor: Abmole

Type: Molecular

SKU: M9898

$368.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
TNO155 is a first-in-class, selective, orally active wild-type SHP2 metamorphosis inhibitor with an IC50 value of 0.011 µM. tNO155 has good water solubility (0.736 mM), moderate lipophilicity (LogP=1.6), high lipophilic efficiency (>6), and no hERG inhibition (IC50 >30 μM) and no phototoxicity. Does not inhibit CYP450.
Casnumber
1801765-04-7
Formula
C18H24ClN7OS
Mw
421.95
Psmiles
CC1OCC2(CCN(CC2)C3=CN=C(SC4=C(Cl)C(=NC=C4)N)C(=N3)N)C1N
Purity
>99%
Solubility
DMSO 100 mg/mL
Target synonyms
TNO-155；Batoprotafib
TNO155

TNO155

$368.00 USD