Tolebrutinib

Vendor: Abmole

Type: Molecular

SKU: M10274

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$149.50 USD
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For research use only — not intended for clinical or diagnostic purposes.
Tolebrutinib

Tolebrutinib

$149.50 USD

THE SCIENCE, IN DETAIL

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Specifications
Bioactivity
Tolebrutinib (SAR442168) is a potent, selective, orally active and blood-brain barrier capable bruton's tyrosine kinase (BTK) inhibitor with IC50 values of 0.4 and 0.7 nM in Ramos B cells and HMC microglia, respectively. Tolebrutinib has an effect on central nervous system immunity. Tolebrutinib can be used in multiple sclerosis (MS) studies.
Casnumber
1971920-73-6
Formula
C26H25N5O3
Mw
455.51
Psmiles
NC1=NC=CC2=C1N(C(=O)N2C3CCCN(C3)C(=O)C=C)C4=CC=C(OC5=CC=CC=C5)C=C4
Purity
>99.0%
Solubility
DMSO 80 mg/mL
Target synonyms
SAR442168; PRN2246
Technical documents

Documents

Coa

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