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TP0427736 HCl

Vendor: Abmole

Type: Molecular

SKU: M20633

$184.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
TP0427736 is a potent inhibitor of ALK5 kinase activity with an IC50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC50 = 836 nM for ALK3). It also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with an IC50 value of 8.68 nM.
Casnumber
864374-00-5
Formula
C14H11ClN4S2
Mw
334.85
Psmiles
Cl.CC1=CSC(=N1)C2=C([NH]C=N2)C3=CC4=C(C=C3)N=CS4
Purity
>99%
Solubility
DMSO 67 mg/mL
תמונת ברירת מחדל

TP0427736 HCl

$184.00 USD