TPR rabbit pAb
Vendor: ELK Biotechnology
SKU: ES12600
Regular price
$148.00 USD
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Regular price
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
Nucleus . Nucleus membrane ; Peripheral membrane protein ; Nucleoplasmic side . Nucleus envelope . Nucleus, nuclear pore complex . Cytoplasm . Cytoplasm, cytoskeleton, spindle . Chromosome, centromere, kinetochore . Nucleus membrane ; Peripheral membrane protein ; Cytoplasmic side . Detected as discrete intranuclear foci with IFI204 (By similarity). In interphase, localizes to the nucleoplasmic side of the nuclear pore complex (NPC) core structure, forming a fibrous structure called the nuclear basket. Detected exclusively to the cytoplasmic margin of NPC (PubMed:7798308). Docking to the inner nucleoplasmic side of the NPC is mediated through binding to nucleoporins. Anchored by NUP153 to the NPC. The assembly of the NPC is a stepwise process in which Trp-containing peripheral structures a
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
7175
Human swiss prot no
P12270
Immunogen
Synthesized peptide derived from human TPR AA range: 2191-2241
Isotype
IgG
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
WB 1:500-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq, Jul 2008],
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Product Citations
Product Citations
More Info
More Info
TPR rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

