Trabectedin

Vendor: Abmole

Type: Molecular

SKU: M21415

$368.00 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid that binds to the minor groove of DNA, blocks stress-induced transcription of proteins, induces DNA backbone cleavage and apoptosis, and increases ROS production in MCF-7 and MDA-MB-453 cells. Trabectedin can be used in soft tissue sarcoma and ovarian cancer studies.
Casnumber
114899-77-3
Formula
C39H43N3O11S
Mw
761.84
Psmiles
CC1=CC2=C(C3C4C5C6=C(C(=C7C(=C6C(N4C(C(C2)N3C)O)COC(=O)C8(CS5)C9=CC(=C(C=C9CCN8)O)OC)OCO7)C)OC(=O)C)C(=C1OC)O
Purity
＞99%
Solubility
DMSO ≥ 60 mg/mL
Target synonyms
Ecteinascidin 743; ET-743
Trabectedin

Trabectedin

$368.00 USD